ISTA 2A tests are for packaged-products 150 lb. (68 kg) or less, and are a combination of basic test elements from ISTA 1A (Non-Simulation Integrity Performance Testing) and advanced test elements from ISTA 3A (General Simulation Performance Testing). Procedure 2A simulates some actual transport hazards such as temperature and humidity. An example would be to test desert-like conditions (60C and 15% RH), which are dry with low humidity, on a packaged-product.
When properly applied, ISTA Procedure 2A will provide tangible benefits of:
| Sequence | Test Type | Standard | Description |
| 1 | Atmospheric Preconditioning | ASTM E171 | Ambient Temperature and Humidity |
| 2 | Atmospheric Conditioning | ASTM D4332 | Controlled Temperature and Humidity |
| 3 | Compression | ASTM D642 | Machine Apply and Release |
| 4 | Vibration | ASTM D999 | Fixed Displacement |
| 5 | Shock | ASTM D5276 | Drop |
| 6 | Vibration | ASTM D999 | Fixed Displacement |